![北京索莱宝科技有限公司](https://img.medsci.cn/85ebba042b5a3efdb9bbe4c9625c9c24badc514d6cbad65dd5a9b5ac96efecac.jpg)
ROCK1 Polyclonal Antibody
产品名称: ROCK1 Polyclonal Antibody
英文名称: ROCK1 Polyclonal Antibody
产品编号: K001838P
产品价格: null
产品产地: 北京市通州区马驹桥联
品牌商标: solarbio
更新时间: 2025-02-08T13:37:52
使用范围:
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073 点击查看
- 传真 : 点击查看
- 邮箱 : 3193328036@qq.com
- 二维码 : 点击查看
Anti-ROCK1 Polyclonal Antibody
品牌:solarbio | 货号:K001838P
英文名称 | Anti-ROCK1 Polyclonal Antibody |
---|---|
别名 | P160ROCK;ROCK-I |
应用 | WB IHC IP |
稀释比例 | WB 1:500-2000. IHC 1:50-100. IP 1:50-100. |
交叉反应 | Human Mouse Rat |
蛋白分子量 | 158kDa |
Gene ID | 6093 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | Recombinant protein of human ROCK1 |
性状 | 液体 |
Public Immunogen Range | Recombinant protein of human ROCK1 |
Subcellular Locations | Cell membrane Cell projection Cytoplasm Golgi apparatus membrane Peripheral membrane protein bleb centriole centrosome cytoskeleton lamellipodium microtubule organizing center ruffle |
Swiss Prot | Q13464 |
克隆类型 | Polyclonal Antibody |
背景资料 | This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. |