Anti-Smad2 Monoclonal Antibody-抗体-抗体-生物在线

Anti-Smad2 Monoclonal Antibody

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产品名称： Anti-Smad2 Monoclonal Antibody

英文名称： Anti-Smad2 Monoclonal Antibody

产品编号： K000096M

产品价格： null

产品产地：北京

品牌商标： Solarbio

更新时间： 2025-02-18T14:23:40

使用范围： WB

北京索莱宝科技有限公司

联系人 : 索莱宝-龚思雨
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产品详情

Anti-Smad2 Monoclonal Antibody  
品牌：solarbio | 货号：K000096M




英文名称 Anti-Smad2 Monoclonal Antibody
宿主 Mouse
别名 hMAD-2;hSMAD2;JV18;JV18-1;MADH2;MADR2
应用 WB ICC
稀释比例 WB 1:500. ICC 1:100.
交叉反应 Human
蛋白分子量 60kDa
Gene ID 4087
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG1
免疫原 Purified recombinant human Smad2 protein fragments expressed in E.coli.
性状 液体
Public Immunogen Range Purified recombinant human Smad2 protein fragments expressed in E.coli.
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q15796
克隆号 6H5-E3-C11
克隆类型 Monoclonal Antibody
背景资料 The protein encoded by this gene belongs to the SMAD,a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C.elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways.This protein mediates the signal of the transforming growth factor (TGF)-beta,and thus regulates multiple cellular processes,such as cell proliferation,apoptosis,and differentiation.This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein.In response to TGF-beta signal,this protein is phosphorylated by the TGF-beta receptors.The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4.The association with SMAD4 is important for the translocation of this protein into the nucleus,where it binds to target promoters and forms a transcription repressor complex with other cofactors.This protein can also be phosphorylated by activin type 1 receptor kinase,and mediates the signal from the activin.Alternatively spliced transcript variants have been observed for this gene.[provided by RefSeq,May 2012]

英文名称	Anti-Smad2 Monoclonal Antibody
宿主	Mouse
别名	hMAD-2;hSMAD2;JV18;JV18-1;MADH2;MADR2
应用	WB ICC
稀释比例	WB 1:500. ICC 1:100.
交叉反应	Human
蛋白分子量	60kDa
Gene ID	4087
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG1
免疫原	Purified recombinant human Smad2 protein fragments expressed in E.coli.
性状	液体
Public Immunogen Range	Purified recombinant human Smad2 protein fragments expressed in E.coli.
Subcellular Locations	Cytoplasm Nucleus
Swiss Prot	Q15796
克隆号	6H5-E3-C11
克隆类型	Monoclonal Antibody
背景资料	The protein encoded by this gene belongs to the SMAD,a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C.elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways.This protein mediates the signal of the transforming growth factor (TGF)-beta,and thus regulates multiple cellular processes,such as cell proliferation,apoptosis,and differentiation.This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein.In response to TGF-beta signal,this protein is phosphorylated by the TGF-beta receptors.The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4.The association with SMAD4 is important for the translocation of this protein into the nucleus,where it binds to target promoters and forms a transcription repressor complex with other cofactors.This protein can also be phosphorylated by activin type 1 receptor kinase,and mediates the signal from the activin.Alternatively spliced transcript variants have been observed for this gene.[provided by RefSeq,May 2012]