ESR1 monoclonal antibody, clone 5D4B1,5D4E3
产品名称： ESR1 monoclonal antibody, clone 5D4B1,5D4E3
英文名称： ESR1 monoclonal antibody, clone 5D4B1,5D4E3
产品编号： MAB8304
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant ESR1.
- Immunogen:
- Recombinant protein corresponding to truncated human ESR1.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG2b
- Storage Buffer:
- In ascites
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:2000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance.
Campbell RA, Bhat-Nakshatri P, Patel NM, Constantinidou D, Ali S, Nakshatri H.J Biol Chem. 2001 Mar 30;276(13):9817-24. Epub 2001 Jan 3.
- 2.
- Activation of estrogen receptor alpha by S118 phosphorylation involves a ligand-dependent interaction with TFIIH and participation of CDK7.
Chen D, Riedl T, Washbrook E, Pace PE, Coombes RC, Egly JM, Ali S.Mol Cell. 2000 Jul;6(1):127-37.
- Entrez GeneID:
- 2099
- Gene Name:
- ESR1
- Gene Alias:
- DKFZp686N23123,ER,ESR,ESRA,Era,NR3A1
- Gene Description:
- estrogen receptor 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq
- Other Designations:
- OTTHUMP00000017718,OTTHUMP00000017719,estrogen receptor alpha
- Related Disease
- Abortion, Habitual
- Abortion, Spontaneous
- Acute Disease
- Adenocarcinoma
- Alveolar Bone Loss
- Alzheimer Disease
- Alzheimer disease
- Amphetamine-Related Disorders
- Anorexia Nervosa
- Antisocial Personality Disorder
- Aortic Aneurysm, Abdominal
- Arteriosclerosis
- Arthritis, Juvenile Rheumatoid
- Asperger Syndrome
- Asthma
- Asthma
- Atherosclerosis
- Atherosclerosis
- Atrial Fibrillation