ACVR1B MaxPab rabbit polyclonal antibody (D01)
产品名称： ACVR1B MaxPab rabbit polyclonal antibody (D01)
英文名称： ACVR1B MaxPab rabbit polyclonal antibody (D01)
产品编号： H00000091-D01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human ACVR1B protein.
- Immunogen:
- ACVR1B (NP_004293.1, 1 a.a. ~ 505 a.a) full-length human protein.
- Sequence:
- MAESAGASSFFPLVVLLLAGSGGSGPRGVQALLCACTSCLQANYTCETDGACMVSIFNLDGMEHHVRTCIPKVELVPAGKPFYCLSSEDLRNTHCCYTDYCNRIDLRVPSGHLKEPEHPSMWGPVELVGIIAGPVFLLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCEMCLSKDKTLQDLVYDLSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEEYQLPYYDLVPSDPSIEEMRKVVCDQKLRPNIPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQLSVQEDVKI
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- ACVR1B MaxPab rabbit polyclonal antibody. Western Blot analysis of ACVR1B expression in HeLa.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of ACVR1B expression in transfected 293T cell line (H00000091-T01) by ACVR1B MaxPab polyclonal antibody.
Lane 1: ACVR1B transfected lysate(56.80 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 91
- GeneBank Accession#:
- NM_004302.3
- Protein Accession#:
- NP_004293.1
- Gene Name:
- ACVR1B
- Gene Alias:
- ACTRIB,ACVRLK4,ALK4,SKR2
- Gene Description:
- activin A receptor, type IB
- Omim ID:
- 601300
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with a cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type IB receptor, composed of 11 exons. Alternative splicing and alternative polyadenylation result in 3 fully described transcript variants. The mRNA expression of variants 1, 2, and 3 is confirmed, and a potential fourth variant contains an alternative exon 8 and lacks exons 9 through 11, but its mRNA expression has not been confirmed. [provided by RefSeq
- Other Designations:
- activin A receptor, type II-like kinase 4,activin A type IB receptor,activin receptor-like kinase 4,serine(threonine) protein kinase receptor R2